Set within the Sciusa Valley near Noli and Spotorno, the 3-bedroom residence occupies the villa’s piano nobile, its principal reception floor, with vaulted ceilings, 18th-century frescoes, private grounds and a swimming pool.

Once home to Sophia Loren and her husband, film producer Carlo Ponti, this secluded villa on Rome’s Appian Way sits above an ancient basalt quarry, with Roman mosaics, 2,000-year-old fragments and a history tied to Cinecittà, Rome’s legendary film studio and the heart of Italy’s postwar cinema.

Portrait artist to European royalty and leading cultural figures, Michele Gordigiani reshaped Striano with architect Luigi Del Moro as a house for painting, music and entertaining. Its extraordinary limonaia draws on the same Florentine garden tradition as the famous grotto at the Boboli Gardens.

Less than an hour from Rome, this restored 19th-century farmhouse sits on nearly 10 acres in the Etruscan countryside. Rebuilt from a ruin by 21-year-old photographer Filippo Chia, it reflects both his family’s Renaissance roots and the international art world he grew up around.

Built in 1702, this historic villa for sale near Milan sits on 25 acres with formal Italian gardens, a 19th-century English park, and a remarkable hidden Secret Garden.

Commissioned by Francesco Burlamacchi, who was executed for plotting to unite Tuscany’s independent republics against Medici rule, the villa later became home to antifascist jurist Paolo Rossi, who helped draft the constitution of modern Italy.

Villa Impero is not a typical private villa. Built in the early 1800s for the Marquis Mazzacorati, it was originally conceived as a Neoclassical reception pavilion for the nearby Villa Aldrovandi ai Camaldoli estate, with frescoed interiors designed for balls, receptions, and formal gatherings.